Serveur d'exploration sur le lymphœdème

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Molecular characterization of antigens of lymphatic filarial parasites

Identifieur interne : 00EB58 ( Main/Exploration ); précédent : 00EB57; suivant : 00EB59

Molecular characterization of antigens of lymphatic filarial parasites

Auteurs : M. E. Selkirk ; D. A. Denham ; F. Partono [Indonésie] ; I. Sutanto [Indonésie] ; R. M. Maizels

Source :

RBID : ISTEX:E4C3AECDA787334947A07327C4C9D7332ACA3C54

Descripteurs français

English descriptors

Abstract

Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of adult worms of each species for the afferent lymphatics. Reproductive activity leads to the release of large numbers of microfilariae, which circulate in the vascular system, and upon ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae (L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the definitive host via the wound and mature to the adult stage over several months, involving two moults, during which the entire nematode exoskeleton (cuticle) is replaced.

Url:
DOI: 10.1017/S003118200008567X


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of adult worms of each species for the afferent lymphatics. Reproductive activity leads to the release of large numbers of microfilariae, which circulate in the vascular system, and upon ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae (L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the definitive host via the wound and mature to the adult stage over several months, involving two moults, during which the entire nematode exoskeleton (cuticle) is replaced.</div>
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