Molecular characterization of antigens of lymphatic filarial parasites
Identifieur interne : 00EB58 ( Main/Exploration ); précédent : 00EB57; suivant : 00EB59Molecular characterization of antigens of lymphatic filarial parasites
Auteurs : M. E. Selkirk ; D. A. Denham ; F. Partono [Indonésie] ; I. Sutanto [Indonésie] ; R. M. MaizelsSource :
- Parasitology [ 0031-1820 ] ; 1986-01.
Descripteurs français
- KwdFr :
- ADN (génétique), ARN (génétique), Animaux, Antigènes d'helminthe (analyse), Antigènes d'helminthe (génétique), Antigènes d'helminthe (immunologie), Brugia (génétique), Brugia (immunologie), Chats, Clonage moléculaire, Facteurs sexuels, Femelle, Filariose lymphatique (immunologie), Filarioses (diagnostic), Filarioses (immunologie), Gerbillinae, Humains, Immunité acquise d'origine maternelle, Immunité active, Immunité innée, Modèles animaux de maladie humaine, Mâle, Réactions croisées, Urée (analogues et dérivés), Wuchereria (immunologie), Wuchereria bancrofti (génétique), Wuchereria bancrofti (immunologie), Électrophorèse sur gel de polyacrylamide, Épitopes.
- MESH :
- analogues et dérivés : Urée.
- analyse : Antigènes d'helminthe.
- diagnostic : Filarioses.
- génétique : ADN, ARN, Antigènes d'helminthe, Brugia, Wuchereria bancrofti.
- immunologie : Antigènes d'helminthe, Brugia, Filariose lymphatique, Filarioses, Wuchereria, Wuchereria bancrofti.
- Animaux, Chats, Clonage moléculaire, Facteurs sexuels, Femelle, Gerbillinae, Humains, Immunité acquise d'origine maternelle, Immunité active, Immunité innée, Modèles animaux de maladie humaine, Mâle, Réactions croisées, Électrophorèse sur gel de polyacrylamide, Épitopes.
English descriptors
- KwdEn :
- Animals, Antigens, Helminth (analysis), Antigens, Helminth (genetics), Antigens, Helminth (immunology), Brugia (genetics), Brugia (immunology), Cats, Cloning, Molecular, Cross Reactions, DNA (genetics), Disease Models, Animal, Electrophoresis, Polyacrylamide Gel, Elephantiasis, Filarial (immunology), Epitopes, Female, Filariasis (diagnosis), Filariasis (immunology), Gerbillinae, Humans, Immunity, Active, Immunity, Innate, Immunity, Maternally-Acquired, Male, RNA (genetics), Sex Factors, Urea (analogs & derivatives), Wuchereria (immunology), Wuchereria bancrofti (genetics), Wuchereria bancrofti (immunology).
- MESH :
- chemical , analogs & derivatives : Urea.
- chemical , analysis : Antigens, Helminth.
- chemical , genetics : Antigens, Helminth, DNA, RNA.
- chemical , immunology : Antigens, Helminth.
- diagnosis : Filariasis.
- genetics : Brugia, Wuchereria bancrofti.
- immunology : Brugia, Elephantiasis, Filarial, Filariasis, Wuchereria, Wuchereria bancrofti.
- Animals, Cats, Cloning, Molecular, Cross Reactions, Disease Models, Animal, Electrophoresis, Polyacrylamide Gel, Epitopes, Female, Gerbillinae, Humans, Immunity, Active, Immunity, Innate, Immunity, Maternally-Acquired, Male, Sex Factors.
Abstract
Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of adult worms of each species for the afferent lymphatics. Reproductive activity leads to the release of large numbers of microfilariae, which circulate in the vascular system, and upon ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae (L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the definitive host via the wound and mature to the adult stage over several months, involving two moults, during which the entire nematode exoskeleton (cuticle) is replaced.
Url:
DOI: 10.1017/S003118200008567X
Affiliations:
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Le document en format XML
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<term>Antigens, Helminth (genetics)</term>
<term>Antigens, Helminth (immunology)</term>
<term>Brugia (genetics)</term>
<term>Brugia (immunology)</term>
<term>Cats</term>
<term>Cloning, Molecular</term>
<term>Cross Reactions</term>
<term>DNA (genetics)</term>
<term>Disease Models, Animal</term>
<term>Electrophoresis, Polyacrylamide Gel</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Epitopes</term>
<term>Female</term>
<term>Filariasis (diagnosis)</term>
<term>Filariasis (immunology)</term>
<term>Gerbillinae</term>
<term>Humans</term>
<term>Immunity, Active</term>
<term>Immunity, Innate</term>
<term>Immunity, Maternally-Acquired</term>
<term>Male</term>
<term>RNA (genetics)</term>
<term>Sex Factors</term>
<term>Urea (analogs & derivatives)</term>
<term>Wuchereria (immunology)</term>
<term>Wuchereria bancrofti (genetics)</term>
<term>Wuchereria bancrofti (immunology)</term>
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<term>ARN (génétique)</term>
<term>Animaux</term>
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<term>Antigènes d'helminthe (génétique)</term>
<term>Antigènes d'helminthe (immunologie)</term>
<term>Brugia (génétique)</term>
<term>Brugia (immunologie)</term>
<term>Chats</term>
<term>Clonage moléculaire</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Filarioses (diagnostic)</term>
<term>Filarioses (immunologie)</term>
<term>Gerbillinae</term>
<term>Humains</term>
<term>Immunité acquise d'origine maternelle</term>
<term>Immunité active</term>
<term>Immunité innée</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Réactions croisées</term>
<term>Urée (analogues et dérivés)</term>
<term>Wuchereria (immunologie)</term>
<term>Wuchereria bancrofti (génétique)</term>
<term>Wuchereria bancrofti (immunologie)</term>
<term>Électrophorèse sur gel de polyacrylamide</term>
<term>Épitopes</term>
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<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Urea</term>
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<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antigens, Helminth</term>
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<term>DNA</term>
<term>RNA</term>
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<term>ARN</term>
<term>Antigènes d'helminthe</term>
<term>Brugia</term>
<term>Wuchereria bancrofti</term>
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<term>Brugia</term>
<term>Filariose lymphatique</term>
<term>Filarioses</term>
<term>Wuchereria</term>
<term>Wuchereria bancrofti</term>
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<term>Elephantiasis, Filarial</term>
<term>Filariasis</term>
<term>Wuchereria</term>
<term>Wuchereria bancrofti</term>
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<term>Cross Reactions</term>
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<term>Epitopes</term>
<term>Female</term>
<term>Gerbillinae</term>
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<term>Sex Factors</term>
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<front><div type="abstract" xml:lang="en">Three species of filarial worms, Wuchereria bancrofti, Brugia malayi and Brugia timori, are the causative agents of lymphatic filariasis in man, defined by the characteristic tropism of adult worms of each species for the afferent lymphatics. Reproductive activity leads to the release of large numbers of microfilariae, which circulate in the vascular system, and upon ingestion by an appropriate mosquito vector, develop through to infective third-stage larvae (L3) within 10–14 days. After a subsequent bloodmeal, the infective larvae enter the definitive host via the wound and mature to the adult stage over several months, involving two moults, during which the entire nematode exoskeleton (cuticle) is replaced.</div>
</front>
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